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NFLHead-to-Head2026 Season

Arizona Cardinals vs San Francisco 49ers · 2026 Season

Last updated: April 15, 2026

1 meetings tracked · closing-line graded

Across 1 2026 season meetings, San Francisco 49ers lead 1-0. Games have averaged 66.0 combined points.

RECORD

0-1

MEETINGS

1

Key Insights

  • ▸San Francisco 49ers lead 1-0 across 1 tracked meetings.
  • ▸Games have averaged 66.0 combined points.

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Frequently Asked Questions

What is the Arizona Cardinals vs San Francisco 49ers record all-time?▾

Across 1 all-time meetings, the San Francisco 49ers lead the series 1-0.

What is the ATS trend in Arizona Cardinals vs San Francisco 49ers games?▾

ATS: Arizona Cardinals are 1-— vs the spread in these matchups. San Francisco 49ers are —-1.

Do Arizona Cardinals vs San Francisco 49ers games go over or under?▾

Over/under: games between Arizona Cardinals and San Francisco 49ers have gone over 1 times and under — times, with an average combined score of 66.0.

When did Arizona Cardinals and San Francisco 49ers last play?▾

See Last Meetings section for detailed score, spread, and total data from the most recent Arizona Cardinals vs San Francisco 49ers games.

Where can I see the 5-year Arizona Cardinals vs San Francisco 49ers history?▾

A 5-year head-to-head page tracks every Arizona Cardinals vs San Francisco 49ers meeting from the last five full seasons. Link at the bottom of this page.

Head-to-head data derived from closing-line game records. Stats update nightly from graded game results.

For informational and entertainment purposes only. Not betting advice. Please gamble responsibly.

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