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MLBHead-to-HeadAll-Time

San Francisco Giants vs St. Louis Cardinals · All-Time

Last updated: April 15, 2026

52 meetings tracked · closing-line graded

Across 52 all-time head-to-head meetings, St. Louis Cardinals lead 28-24. Games have averaged 9.2 combined points.

RECORD

24-28

MEETINGS

52

ATS

16-16

O / U

19-13

Key Insights

  • ▸St. Louis Cardinals lead 28-24 across 52 tracked meetings.
  • ▸Games have averaged 9.2 combined points.
  • ▸Strong Over trend: 19-13 O/U.

Year-by-Year Record

SeasonGamesSan Francisco GiantsSt. Louis CardinalsATSO / UAvg Total
20266515-14-28.7
20256243-33-39.5
20246151-55-19.8
20237615-23-49.0
20227342-54-310.7
2021624——7.0
2019734——8.3
2018725——10.3

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Frequently Asked Questions

What is the San Francisco Giants vs St. Louis Cardinals record all-time?▾

Across 52 all-time meetings, the St. Louis Cardinals lead the series 28-24.

What is the ATS trend in San Francisco Giants vs St. Louis Cardinals games?▾

ATS: San Francisco Giants are 16-16 vs the spread in these matchups. St. Louis Cardinals are 16-16.

Do San Francisco Giants vs St. Louis Cardinals games go over or under?▾

Over/under: games between San Francisco Giants and St. Louis Cardinals have gone over 19 times and under 13 times, with an average combined score of 9.2.

When did San Francisco Giants and St. Louis Cardinals last play?▾

See Last Meetings section for detailed score, spread, and total data from the most recent San Francisco Giants vs St. Louis Cardinals games.

Where can I see the 5-year San Francisco Giants vs St. Louis Cardinals history?▾

A 5-year head-to-head page tracks every San Francisco Giants vs St. Louis Cardinals meeting from the last five full seasons. Link at the bottom of this page.

Data coverage: Trendline's head-to-head records include closing-line-graded games from 2018–2026. Older meetings aren't in this dataset yet.

Head-to-head data derived from closing-line game records. Stats update nightly from graded game results.

For informational and entertainment purposes only. Not betting advice. Please gamble responsibly.

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