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MLBHead-to-HeadAll-Time

Houston Astros vs St. Louis Cardinals · All-Time

Last updated: April 15, 2026

15 meetings tracked · closing-line graded

Across 15 all-time head-to-head meetings, St. Louis Cardinals lead 8-7. Games have averaged 9.9 combined points.

RECORD

7-8

MEETINGS

15

ATS

5-7

O / U

8-4

Key Insights

  • ▸St. Louis Cardinals lead 8-7 across 15 tracked meetings.
  • ▸Games have averaged 9.9 combined points.
  • ▸St. Louis Cardinals have been the better ATS side (7-5).
  • ▸Strong Over trend: 8-4 O/U.

Year-by-Year Record

SeasonGamesHouston AstrosSt. Louis CardinalsATSO / UAvg Total
2026303——12.3
20253121-21-26.0
20243212-12-110.0
20233212-12-112.3
2019321——8.7

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Frequently Asked Questions

What is the Houston Astros vs St. Louis Cardinals record all-time?▾

Across 15 all-time meetings, the St. Louis Cardinals lead the series 8-7.

What is the ATS trend in Houston Astros vs St. Louis Cardinals games?▾

ATS: Houston Astros are 5-7 vs the spread in these matchups. St. Louis Cardinals are 7-5.

Do Houston Astros vs St. Louis Cardinals games go over or under?▾

Over/under: games between Houston Astros and St. Louis Cardinals have gone over 8 times and under 4 times, with an average combined score of 9.9.

When did Houston Astros and St. Louis Cardinals last play?▾

See Last Meetings section for detailed score, spread, and total data from the most recent Houston Astros vs St. Louis Cardinals games.

Where can I see the 5-year Houston Astros vs St. Louis Cardinals history?▾

A 5-year head-to-head page tracks every Houston Astros vs St. Louis Cardinals meeting from the last five full seasons. Link at the bottom of this page.

Data coverage: Trendline's head-to-head records include closing-line-graded games from 2019–2026. Older meetings aren't in this dataset yet.

Head-to-head data derived from closing-line game records. Stats update nightly from graded game results.

For informational and entertainment purposes only. Not betting advice. Please gamble responsibly.

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