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MLBHead-to-HeadAll-Time

Houston Astros vs San Diego Padres · All-Time

Last updated: April 15, 2026

21 meetings tracked · closing-line graded

Across 21 all-time head-to-head meetings, San Diego Padres lead 12-9. Games have averaged 8.6 combined points.

RECORD

9-12

MEETINGS

21

ATS

7-5

O / U

5-6

Key Insights

  • ▸San Diego Padres lead 12-9 across 21 tracked meetings.
  • ▸Games have averaged 8.6 combined points.
  • ▸Houston Astros have been the better ATS side (7-5).

Year-by-Year Record

SeasonGamesHouston AstrosSan Diego PadresATSO / UAvg Total
20263122-11-17.7
20253212-11-26.7
20243121-2—5.0
20233212-1—13.0
2021312——14.3
2020303——10.0
2018321——3.7

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Frequently Asked Questions

What is the Houston Astros vs San Diego Padres record all-time?▾

Across 21 all-time meetings, the San Diego Padres lead the series 12-9.

What is the ATS trend in Houston Astros vs San Diego Padres games?▾

ATS: Houston Astros are 7-5 vs the spread in these matchups. San Diego Padres are 5-7.

Do Houston Astros vs San Diego Padres games go over or under?▾

Over/under: games between Houston Astros and San Diego Padres have gone over 5 times and under 6 times, with an average combined score of 8.6.

When did Houston Astros and San Diego Padres last play?▾

See Last Meetings section for detailed score, spread, and total data from the most recent Houston Astros vs San Diego Padres games.

Where can I see the 5-year Houston Astros vs San Diego Padres history?▾

A 5-year head-to-head page tracks every Houston Astros vs San Diego Padres meeting from the last five full seasons. Link at the bottom of this page.

Data coverage: Trendline's head-to-head records include closing-line-graded games from 2018–2026. Older meetings aren't in this dataset yet.

Head-to-head data derived from closing-line game records. Stats update nightly from graded game results.

For informational and entertainment purposes only. Not betting advice. Please gamble responsibly.

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