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MLBHead-to-HeadAll-Time

Cleveland Guardians vs San Diego Padres · All-Time

Last updated: April 15, 2026

16 meetings tracked · closing-line graded

Across 16 all-time head-to-head meetings, San Diego Padres lead 10-6. Games have averaged 7.7 combined points.

RECORD

6-10

MEETINGS

16

ATS

5-9

O / U

4-10

Key Insights

  • ▸San Diego Padres lead 10-6 across 16 tracked meetings.
  • ▸Games have averaged 7.7 combined points.
  • ▸San Diego Padres have been the better ATS side (9-5).
  • ▸Strong Under trend: 4-10 O/U.

Year-by-Year Record

SeasonGamesCleveland GuardiansSan Diego PadresATSO / UAvg Total
20263121-21-28.0
2025303—1-27.7
20243121-2—5.7
20233121-22-19.3
2022431——7.8

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Frequently Asked Questions

What is the Cleveland Guardians vs San Diego Padres record all-time?▾

Across 16 all-time meetings, the San Diego Padres lead the series 10-6.

What is the ATS trend in Cleveland Guardians vs San Diego Padres games?▾

ATS: Cleveland Guardians are 5-9 vs the spread in these matchups. San Diego Padres are 9-5.

Do Cleveland Guardians vs San Diego Padres games go over or under?▾

Over/under: games between Cleveland Guardians and San Diego Padres have gone over 4 times and under 10 times, with an average combined score of 7.7.

When did Cleveland Guardians and San Diego Padres last play?▾

See Last Meetings section for detailed score, spread, and total data from the most recent Cleveland Guardians vs San Diego Padres games.

Where can I see the 5-year Cleveland Guardians vs San Diego Padres history?▾

A 5-year head-to-head page tracks every Cleveland Guardians vs San Diego Padres meeting from the last five full seasons. Link at the bottom of this page.

Data coverage: Trendline's head-to-head records include closing-line-graded games from 2022–2026. Older meetings aren't in this dataset yet.

Head-to-head data derived from closing-line game records. Stats update nightly from graded game results.

For informational and entertainment purposes only. Not betting advice. Please gamble responsibly.

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